杜会龙

  • 个人简介

 

 

一、简历

杜会龙,河北大学生命科学学院,教授,博士生导师,中国植物学会理事,JIPB编委,主要从事燕麦基因组进化与表型可塑性的遗传学基础和燕麦胁迫响应与生长发育平衡的分子调控机制研究,以第一作者或通讯作者(含共同)在Cell(2020,2021,2021),Nature Communications(2017,2019,2023),Molecular Plant(2017,2020),PNAS(2023),Plant Communications(2023),Journal of Integrative Plant Biology(2023),SCIENCE CHINA Life Sciences(2019,2020,2021),Horticulture Research(2023),BMC Biology(2023)和JGG(2022)等期刊发表论文多篇,目前主持农业重大科技项目、燕赵青年科学家、国家自然科学基金、中国科协青年人才托举工程、河北省优秀青年基金等项目。

二、学习工作经历

2010.09-2014.06河北大学 生物信息学 本科

2014.09-2020.07中科院遗传与发育生物学研究所 生物信息学 博士

2020.09至今 河北大学 生命科学学院 教授

三、承担项目

1)农业重大科技项目,涉密项目,NK2022140101,2022.01-2026.12,400万,主持,在研;

2)河北省自然科学基金委,燕赵青年科学家项目,野燕麦盐碱胁迫响应相关基因资源的挖掘与利用,C2023201074,2023.07-2027.12,100万,主持,在研;

3)中国科学技术协会,青年托举人才工程项目,高杂合植物图形基因组构建及功能模块开发,2022.01-2024.12,45万,主持,在研;

4)国家自然科学基金委,青年基金项目,基于甜荞与苦荞基因组的荞麦非生物胁迫抗性、芦丁生物合成及自交不亲和性机制研究,32100500,2022.01-2024.12,30万,主持,在研;

5)河北省自然科学基金委,优秀青年项目,基于三维基因组调控图谱和基因共表达网络挖掘水稻杂种优势的调控位点及遗传机制解析,C2021201048,2021.07-2023.12,20万,主持,在研;

四、获得的人才称号

1)中国科协第七届青年人才托举工程;

2)河北省燕赵青年科学家。

 

针对我国高产、优质、耐逆饲用燕麦品种的匮乏和遗传信息的严重不足等问题,本课题组拟通过广泛收集全球范围内的野生和栽培燕麦种质资源,构建全球燕麦种质资源多样性中心,利用基因组学、群体遗传学、系统进化生物学和多组学等分析方法,推断燕麦的起源与传播历史,探究燕麦群体内的遗传多样性,从而揭示燕麦基因组进化与表型可塑性的遗传学基础(生物信息学);进一步结合分子生物学等技术手段挖掘与燕麦抗性、产量等重要农艺性状相关的功能基因,解析燕麦非生物胁迫响应与生长发育平衡的调控网络和分子机制(分子生物学);并基于基因编辑和杂交等技术实现燕麦的快速从头驯化和定向改造,从而选育高产优质耐逆的燕麦新品种(分子育种)。
2023年度发表论文:
1. Zhang, H.#, He, Q.#, Xing, L., Wang, R., Wang, Y., Liu, Y., Zhou, Q., Li, X., Jia, Z., Liu, Z., Miao, Y., Lin, T., Li, W., Du. H.* The haplotype-resolved genome assembly of autotetraploid rhubarb Rheum officinale provides insights into its genome evolution and massive accumulation of anthraquinones. 2023. Plant Communications. 26:100677. doi: 10.1016/j.xplc.2023.100677. Epub ahead of print. PMID: 37634079. (IF: 10.5,中科院一区);
2. He, Q.#, Ma, D.#, Li, W., Xing, L., Zhang, H., Wang, Y., Du, C., Li, X., Jia, Z., Li, X., Liu, J., Liu, Z., Miao, Y., Feng, R., Lv, Y., Wang, M., Lu, H., Li, X., Xiao, Y., Wang, R., Liang, H., Zhou, Q., Zhang, L.*, Liang, C.*, Du, H.* 2023. High-quality Fagopyrum esculentum genome provides insights into the flavonoid accumulation among different tissues and self-incompatibility. Journal of Integrative Plant Biology. 65(6):1423-1441. (IF: 11.4,中科院一区);
3. Wang, R.#, Li, W., He, Q., Zhang, H., Wang, M., Zheng, X., Liu, Z., Wang, Y., Du, C., Du, H.*, Xing, L.* 2023. The genome of okra (Abelmoschus esculentus) provides insights into its genome evolution and high nutrient content. Horticulture Research. 10(8):uhad120. doi: 10.1093/hr/uhad120. (IF: 8.7,中科院一区);
4. Li, T.#, Tang, S.#, Li, W.#, Zhang, S., Wang, J., Pan, D., Lin, Z., Ma, X., Chang, Y., Liu, B., Sun, J., Wang, X., Zhao, M., You, C., Luo, H., Wang, M., Ye, X., Zhai, J., Shen, Z., Du, H.*, Song, X.*, Huang, G.*, Cao, X.* 2023. Genome evolution and initial breeding of the Triticeae grass Leymus chinensis dominating the Eurasian Steppe. Proc Natl Acad Sci U S A. 120(44):e2308984120. doi: 10.1073/pnas.2308984120. (IF:11.1,中科院一区);
5. Xing, L.#, Wang, M.#, He, Q., Zhang, H., Liang, H., Zhou, Q., Liu, Y., Liu, Z., Wang, Y., Du, C., Xiao, Y., Liu, J., Li, W., Liu, G.*, Du, H.* 2023. Differential subgenome expression underlies biomass accumulation in allotetraploid Pennisetum giganteum. BMC Biology. 21(1):161. doi: 10.1186/s12915-023-01643-w. (IF: 5.4,中科院二区,JCR一区);
6. Chao, J.#, Wu, S.#, Shi, M.#, Xu, X.#, Gao, Q.#, Du, H.#, Gao, B., Guo, D., Yang, S., Zhang, S., Li, Y., Fan, X., Hai, C., Kou, L., Zhang, J., Wang, Z., Li, Y., Xue, W., Xu, J., Deng, X., Huang, X., Gao, X., Zhang, X., Hu, Y., Zeng, X., Li, W., Zhang, L., Peng, S., Wu, J., Hao, B., Wang, X., Yu, H., Li, J.*, Liang, C.*, Tian, WM*. 2023. Genomic insight into domestication of rubber tree. Nature Communications. 14(1):4651. doi: 10.1038/s41467-023-40304-y. (IF: 16.6,中科院一区);
7. He, Q.#, Tang, S.#, Zhi, H.#, Chen, J.#, Zhang, J., Liang, H., Alam, O., Li, H., Zhang, H., Xing, L., Li, X., Zhang, W., Wang, H., Shi, J., Du, H., Wu, H., Wang, L., Yang, P., Xing, L., Yan, H., Song, Z., Liu, J., Wang, H., Tian, X., Qiao, Z., Feng, G., Guo, R., Zhu, W., Ren, Y., Hao, H., Li, M., Zhang, A., Guo, E., Yan, F., Li, Q., Liu, Y., Tian, B., Zhao, X., Jia, R., Feng, B., Zhang, J., Wei, J., Lai, J., Jia, G., Purugganan, M.*, Diao, X.* 2023. A graph-based genome and pan-genome variation of the model plant Setaria. Nature Genetics. 55(7):1232-1242. doi: 10.1038/s41588-023-01423-w. (IF: 30.8,中科院一区);
8. Wang, W., Qin, L., Zhang, W., Tang, L., Zhang, C., Dong, X., Miao, P., Shen, M., Du, H., Cheng, H., Wang, K., Zhang, X., Su, M., Lu, H., Li, C., Gao, Q., Zhang, X., Huang, Y., Liang, C., Zhou, JM, Chen, YH. 2023. WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance. Cell. 186(12):2656-2671.e18. doi: 10.1016/j.cell.2023.05.023. (IF: 64.5,中科院一区);
9. Hu, R., Li, X., Hu, Y., Zhang, R., Lv, Q., Zhang, M., Sheng, X., Zhao, F., Chen, Z., Ding, Y., Yuan, H., Wu, X., Xing, S., Yan, X., Bao, F., Wan, P., Xiao, L., Wang, X., Xiao, W., Decker, EL., van, Gessel, N., Renault, H., Wiedemann, G., Horst, NA., Haas, FB., Wilhelmsson, PKI., Ullrich, KK., Neumann, E., Lv, B., Liang, C., Du, H., Lu, H., Gao, Q., Cheng, Z., You, H., Xin, P., Chu, J., Huang, CH., Liu, Y., Dong, S., Zhang, L., Chen, F., Deng, L., Duan, F., Zhao, W., Li, K., Li, Z., Li, X., Cui, H., Zhang, YE., Ma, C., Zhu, R., Jia, Y., Wang, M., Hasebe, M., Fu, J., Goffinet, B., Ma, H., Rensing, SA., Reski, R., He, Y. 2023. Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet. Cell. 2023 Aug 17;186(17):3558-3576.e17. doi: 10.1016/j.cell.2023.07.003. (IF: 64.5,中科院一区);
其他年份论文代表作:
1. Du, H., Liang, C. 2019. Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads. Nature Communications, 10,5360. (IF: 16.6,中科院一区); 2. Du, H.#, Yu, Y.#, Ma, Y.#, Gao, Q.#, Cao, Y.#, Chen, Z., Ma, B., Qi, M., Li, Y., Zhao, X., Wang, J., Liu, K., Qin, Peng., Yang, X., Zhu, L., Li, S.*, Liang, C.* 2017. Sequencing and de novo assembly of a near complete indica rice genome. Nature Communications, 8,15324. (IF: 16.6,中科院一区);
3. Liu, Y.#, Du, H.#, Li, P., Shen, Y., Peng, H., Liu, S., Zhou, G., Zhang, H., Liu, Z., Shi, M., Huang, X., Li, Y., Zhang, M., Wang, Z., Zhu, B., Han, B., Liang, C.*, Tian, Z.* 2020. Pan-Genome of Wild and Cultivated Soybeans. Cell, 182,162-176. (IF: 64.5,中科院一区);
4. Shen, C.#, Du, H.#, Chen, Z.#, Lu, H.#, Zhu, F., Chen, H., Meng, X., Liu, Q., Liu, P., Zheng, L., Li, X., Dong, J.*, Liang, C.*, Wang, T.* 2020. The Chromosome-Level Genome Sequence of the Autotetraploid Alfalfa and Resequencing of Core Germplasms Provide Genomic Resources for Alfalfa Research. Molecular Plant, 13,1250-1261. (IF: 27.5,中科院一区);
5. Qin, P.#*, Lu, H.#, Du, H.#, Wang, H.#, Chen, W.#, Chen, Z.#, He, Q., Ou, S., Zhang, H., Li, X., Li, X., Li, Y., Liao, Y., Gao, Q., Tu, B., Yuan, H., Ma, B., Wang, Y., Qian, Y., Fan, S., Li, W., Wang, J., He, M., Yin, J., Li, T., Jiang, N., Chen, X., Liang, C.*, Li, S.* 2021. Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations. Cell. 184, 3542-3558. (IF: 64.5,中科院一区);
6. Yu, H.#, Lin, T.#, Meng, X.#, Du, H.#, Zhang, J.#, Liu, G., Chen, M., Jing, Y., Kou, L., Li, X., Gao, Q., Liang, Y., Liu, X., Fan, Z., Liang, Y., Cheng, Z., Chen, M., Tian, Z., Wang, Y., Chu, C., Zuo, J., Wan, J., Qian, Q., Han, B., Zuccolo, A., Wing, RA,, Gao, C.*, Liang, C.*, Li, J.* 2021. A route to de novo domestication of wild allotetraploid rice. Cell. 184(5):1156-1170.e14. doi: 10.1016/j.cell.2021.01.013. (IF: 64.5,中科院一区)。

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