Webpage in English: https://orcid.org/0000-0002-1238-3948
研究团队：https://smkxxy.hbu.cn/kytd2/kytde71/tdcy.htm
工作经历：
2018年至今，教授，研究员，博士生导师，河北大学
2008–2010年，访问学者，瑞士苏黎世大学（University of Zürich）/瑞士生物信息研究所（Swiss Institute of Bioinformatics）
2006–2018年，副研究员，中国科学院动物研究所，农业虫害鼠害综合治理研究国家重点实验室
2003–2005，助理研究员，中国科学院动物研究所，农业虫害鼠害综合治理研究国家重点实验室
教育经历：
2005-2006年，博士后，芝加哥大学(The University of Chicago)
2000–2003年，研究生，博士，中国科学院动物研究所
1997–2000年，研究生，硕士，华中农业大学
1993–1997年，本科，学士，长江大学
本科与研究生教学：
《遗传学》，主讲，本科生课程
《生态与功能基因组学》，主讲，研究生课程
《生命科学导论》，参讲，本科生课程
《生命科学研究进展》，参讲，本科生课程
《动物学研究进展》，参讲，研究生课程
《生命科学前沿研究》，参讲，研究生课程
《分子生物学》，副主编，科学出版社，2024年，本科生教材
《生态基因组学》，参编，科学出版社，2019年，研究生教材
科学研究领域/方向：
研究生物响应/适应极端环境的生理与行为机理。针对氧气、水或温度等因子异常导致的生物体健康效应，开展动物生理学、行为学及生态基因组学、进化遗传学等前沿交叉学科研究，解析生物对环境压力的生理生化或神经行为响应规律及其分子和遗传调节机制。
主持国家级科研项目：
1. 科技部重点研发计划子课题(No. 2022YFD1400503)，“蝗虫群聚跨代传递的环境适应机制”，2022.09-2025.12，60万
2. 国家自然科学基金委面上项目（No: 31872304），“转座因子通过介导长非编码RNA的表达调控飞蝗行为可塑性”，2019-2022年，62万
3. 国家自然科学基金委国际（中国-以色列）合作和交流项目（No：31661143048），“高原低氧环境下昆虫呼吸系统的适应性进化及其遗传机制研究”，2017-2019年，167万
4. 国家自然科学基金委面上项目（No：31472048），“飞蝗型变可塑性的父性遗传及其表观遗传机制研究”，2015-2018年，84万
5. 国家自然科学基金委重大研究计划培育项目(No：91331106），“飞蝗对青藏高原低氧极端环境遗传适应的多基因互作机”，2014-2016年，100万
6. 国家自然科学基金委面上项目（No：31172148），“分子伴侣蛋白Hsp90 对飞蝗滞育特征进化的调控”，2012-2015年，62万
7. 国家自然科学基金委面上项目（No：30970343），“斑潜蝇生态适应与热激蛋白基因表达的进化”，2010-2012年，29万
8. 国家自然科学基金委面上项目（No：30470291），“温室对斑潜蝇温度胁迫耐受性地理分化的调节及其生态学机制”，2005-2007年，20万
9. 科技部“973”项目子课题（No：2012CB114103），“飞蝗对温度等环境因子变化的适应机制”，2012 - 2016年，250万
10. 科技部“973”项目子课题（No：2006CB102002），“斑潜蝇对环境胁迫的适应机制”，2006 - 2011年，126万
11. 其他： 河北省高校百名优秀创新人才支持计划（no. SLRC2019019），省级，2019-2021年，20万
代表性论文 (*通讯作者，#共同贡献作者)
1. Shen Gao, Fei Zheng, Lei Yue, Bing Chen*. 2024. Chronic cadmium exposure impairs flight behavior by dampening flight muscle carbon metabolism in bumblebees. Journal of Hazardous Materials, 133628. https://doi.org/10.1016/j.jhazmat.2024.133628.
2. Xianliang Huang#, Qing Li#, Yanan Xu, # Ang Li#, Shanzheng Wang, Yusheng Chen, Chunrui Zhang, Xia Zhang, Hailin Wang, Cong Lv, Baofa Sun, Shaoqin Li, Le Kang*, Bing Chen*. 2024. A neural m6A pathway regulates behavioral aggregation in migratory locusts. SCIENCE CHINA Life Sciences 12, DOI: 10.1007/s11427-023-2476-1
3. Bing Chen*#, Xiwen Tong#, Xia Zhang, Wanying Gui, Guoming Ai, Lihua Huang, Ding Ding, Jiangxu Zhang, Le Kang*. 2022. Sulfation modification of dopamine in brain regulates aggregative behavior of animals. National Science Review 9(4), DOI: 10.1093/nsr/nwab163
4. Ding Ding, Jie Zhang, Baozhen Du, Xuanzhao Wang, Li Hou, Siyuan Guo, Bing Chen*, Le Kang*. 2022. Non-canonical function of a Hif-1α splice variant contributes to the sustained flight of locusts. eLife, 11, e74554, DOI: 10.7554/eLife.74554
5. Ding Ding, Guangjian Liu, Li Hou, Wanying Gui, Bing Chen*, Le Kang*. 2018. Genetic variation in PTPN1 contributes to metabolic adaptation to high-altitude hypoxia in Tibetan migratory locusts. Nature Communications, 9(1): 4991
6. Bing Chen*, Bo Zhang, Lingling Xu, Qing Li, Feng Jiang, Pengchen Yang, Yanan Xu, and Le Kang*. 2017. Transposable element-mediated balancing selection at Hsp90 underlies embryo developmental variation. Molecular Biology and Evolution, 34(5), 1127-1139
7. Xia Zhang, Yanan Xu, Bing Chen*, Le Kang*. 2020. Long noncoding RNA PAHAL modulates locust behavioural plasticity through the feedback regulation of dopamine biosynthesis. PLoS Genetics, 16(4): e1008771. DOI: 10.1371/journal.pgen.1008771.
8. Bing Chen*, Martin E. Feder, Le Kang*. 2018. Evolution of heat‐shock protein expression underlying adaptive responses to environmental stress. Molecular Ecology, 27(15): 3040-3054
9. Boyang Guo#, Ting Li#, Lingyan Wang, Fengsong Liu, and Bing Chen*. 2023. Long non-coding RNAs regulate heavy metal-induced apoptosis in embryo-derived cells. Environmental Pollution, 121956. DOI: 10.1016/j.envpol.2023.121956.
10. Fei Zheng, Xin Guo, Mingyang Tang, Dong Zhu, Hongtao Wang, Xiaoru Yang, Bing Chen*. 2023. Variation in pollution status, sources, and risks of soil heavy metals in regions with different levels of urbanization. Science of the Total Environment, 866, 161355.
11. Xia Zhang, Ya´nan Zhu, Bing Chen*, Le Kang*. 2022. A Gypsy element contributes to the nuclear retention and transcriptional regulation of the resident lncRNA in locusts. RNA Biology 19, 206-220
12. Bing Chen#, Shaoqin Li#, Qiang Ren, Xiwen Tong, Xia Zhang, Le Kang*. 2015. Paternal epigenetic effects of population density on locust phase-related characteristics associated with heat-shock protein expression. Molecular Ecology, 24(4): 851-62
13. Xinyue Gu, Yan Zhao, Yun Su, Jiajiao Wu, Ziya Wang, Juntao Hu, Lijun Liu, Zihua Zhao, Ary A. Hoffmann*, Bing Chen*, Zhihong Li*. 2019. A transcriptional and functional analysis of heat hardening in two invasive fruit fly species, Bactrocera dorsalis and Bactrocera correcta. Evolutionary Applications, 12(6): 1147-1163
14. Xianliang Huang, Qianli Du, Lijing Wang, Bing Chen*. 2022. Impacts of oxygen deficiency on embryo life-history traits of migratory locust Locusta migratoria from low and high altitudes. Insect Science, DOI: 10.1111/1744-7917.13129
15. Zimeng Song, Sangzi Ze, Chunxiang Liu, and Bing Chen*. 2023. New insights into the genetic structure of the outbreak-prone bamboo grasshoppers. Frontiers in Ecology and Evolution, 11, DOI: 10.3389/fevo.2023.1062857
16. Jihai Gu, Dongdong Lin, Yanyang Sun, Yongzhi Guo, Bing Chen, Yuming Zhang, Fengsong Liu. 2022. Integrating transcriptome and physiological analysis to reveal the essential responses of Daphnia magna to antimony trioxide nanoparticle. Journal of Hazardous Materials, 437, 129303, DOI: 10.1016/j.jhazmat.2022.129303
17. Fei Zheng, Xin-Li An, Guo-Wei Zhou, Dong Zhu, Roy Neilson, Bing Chen, Xiao-Ru Yang. 2022. Mite gut microbiome and resistome exhibited species-specific and dose-dependent effect in response to oxytetracycline exposure. Science of The Total Environment 807, DOI: 10.1016/j.scitotenv.2021.150802
18. Fei Zheng, Guo-Wei Zhou, Dong Zhu, Roy Neilson, Yong-Guan Zhu, Bing Chen, Xiao-Ru Yang*. 2022. Does plant identity affect the dispersal of resistomes above and below ground? Environmental Science & Technology. 56, 21, 14904–14912, DOI: 10.1021/acs.est.1c08733
19. Bing Chen*, Chunyan Jiang, Siyuan Guo, Kun Guo, Shuguang Hao. 2021. Phenological asynchrony is associated with diapause program and Heat Shock Protein expression in three grasshopper species in the Inner Mongolian Steppe. Frontiers in Ecology & Evolution 9, 743872.
20. Ting Li, Bing Chen, Pengcheng Yang, Depin Wang, Baozhen Du, Le Kang*. 2020. Long noncoding RNA derived from lncRNA–mRNA co-expression networks modulates the locust phase change. Genomics, Proteomics & Bioinformatics, DOI: 10.1016/j.gpb.2020.05.001
21. Lin Hu, Wanying Gui, Bing Chen*, Li Chen*. 2019. Transcriptome profiling of maternal stress-induced wing dimorphism in pea aphids. Ecology and Evolution 9: 11848–11862.
22. Bing Chen#, Ronghui Ma#, and Le Kang*. 2017. Aerobic respiration by hemocyanin in the embryo of the migratory locust. Insect Molecular Biology, 26(4): 461-468.
23. Phyllis Weintraub, Sonja Scheffer, Diedrich Visser, ...Bing Chen(17), Helga Blanco Metzler. 2017. The Invasive Liriomyza huidobrensis (Diptera: Agromyzidae): understanding its pest status and management globally. Journal of Insect Science, 17: 28-28
24. Ruben Martin-Blazquez, Bing Chen, Le Kang, Mohammed Bakkali. 2017. Evolution, expression and association of the chemosensory protein genes with the outbreak phase of the two main pest locusts. Scientific Reports, 7: 6653.
25. Bing Chen#, Yi Zhang#, Xia Zhang, Shili Jia, Shuang Chen, Le Kang*. 2016. Genome-wide identification and developmental expression profiling of long noncoding RNAs during Drosophila metamorphosis. Scientific Reports 6: 23330
26. Bing Chen#, Ronghui Ma#, Guolan Ma#, Xiaojiao Guo, Xiwen Tong, Guowen Tang, Le Kang*. 2015. Haemocyanin is essential for embryonic development and survival in the migratory locust. Insect Molecular Biology, 24(5): 517-527
27. Xiwen Tong#, Bing Chen#, Li-Hua Huang, Qi-Li Feng, Le Kang*. 2015. Proteomic analysis reveals that COP9 signalosome complex subunit 7A (CSN7A) is essential for the phase transition of migratory locust. Scientific Reports, 5:12542
28. Juntao Hu, Bing Chen*, Zhihong Li*. 2014. Thermal plasticity is related to the hardening response of heat shock protein expression in two Bactrocera fruit flies. Journal of Insect Physiology, 67:105-113
29. Xianhui Wang, Xiaodong Fang, Pengcheng Yang, …..., Bing Chen(21st), et al. 2014. The locust genome provides insight into swarm formation and long-distance flight. Nature Communications, 5:2957
30. Yuan Luo, Xianhui Wang, Wang, X., Dan Yu, Bing Chen, Le Kang*. 2013. Differential responses of migratory locusts to systemic RNA interference via double-stranded RNA injection and feeding. Insect Molecular Biology, 22: 574
31. Zhengyu Zhang, Bing Chen, Dejian Zhao, Le Kang*. 2013. Functional modulation of mitochondrial cytochrome c oxidase underlies adaptation to high-altitude hypoxia in Tibetan migratory locust. Proceedings of the Royal Society B: Biological Sciences, 280:20122758
32. Bing Chen, Andreas Wagner*. 2012. Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations. BMC Evolutionary Biology, 12:25
33. Bing Chen#, Tieliu Jia#, Ronghui Ma, Bo Zhang, Le Kang*. 2011. Evolution of Hsp70 gene expression: A role of changes in AT-richness within promoters. PLoS One 6(5): e20308
34. Le Kang*, Bing Chen, Jianing Wei, and Tong-Xian Liu. 2009. Roles of Thermal Adaptation and Chemical Ecology in Liriomyza Distribution and Control. Annual Review of Entomology, 54: 127-45
35. Fu Zhao, Bing Chen, Yong Wang, Fen Zhu, Chao-Liang Lei. 2009. Eicosanoids mediate nodulation reactions to bacterial Escherichia coli K 12 infections in larvae of the oriental blowfly, Chrysomya megacephala. Insect Science, 16 (5), 387–392
36. Bing Chen, Victoria Shilova, Olga Zatsepina, Michael Evgenev, Martin E. Feder*. 2008. Location of P element insertions in the proximal promoter region of Hsp70A is consequential for gene expression and correlated with fecundity in Drosophila melanogaster. Cell Stress & Chaperones, 13(1): 11-17
37. Bing Chen, Jean-Claude Walser, Teresa Rodgers, Rafal Sobota, Molly Burke, Michael Rose, and Martin Feder*. 2007. Abundant, diverse, and consequential P element segregate in promoters of small heat-shock genes in Drosophila populations. Journal of Evolutionary Biology, 20(5): 2056-2066
38. Li-Hua Huang#, Bing Chen# and Le Kang*. 2007. Impact of mild temperature hardening on thermotolerance, fecundity, and Hsp gene expression in Liriomyza huidobrensis. Journal of Insect Physiology, 53：1199-1205
39. Walser JC, Bing Chen, and Martin E. Feder*. 2006. Heat-shock promoters: Targets for evolution by P transposable elements in Drosophila. PLoS Genetics, 2: e165
40. Shilova Victoria, David Garbuz, Elena Myasniankina, Bing Chen, Michel Evgen’ev, Martin Feder, and Olga Zatsepina. 2006. Remarkable site specificity of local transposition into the hsp70 promoter of Drosophila melanogaster. Genetics, 173: 809-820
41. Bing Chen and Le Kang*. 2005. Can greenhouses eliminate the development of cold resistance of the leafminers? Oecologia, 144: 187-195
42. Bing Chen and Le Kang*. 2005. Implication of pupal cold tolerance for the northern over-wintering range limit of the leafminer Liriomyza sativae (Dipera: Agromyzidae) in China. Applied Entomology and Zoology, 40(3): 437-446
43. Bing Chen and Le Kang*. 2005. Insect population differentiation in response to environmental thermal stress. Science China-Life Sciences, 15(4): 289-296
44. Bing Chen and Le Kang*. 2004. Variation in cold hardiness of Liriomyza huidobrensis (Dipera: Agromyzidae) along latitudinal gradients. Environmental Entomology, 33(2): 155-164
45. Bing Chen and Le Kang*. 2002. Cold hardiness and supercooling capacity in the pea leafminer Liriomyza huidobrensis. Cryoletters, 23(3): 173-182
46. 陈兵, 骆家宇. 2023. 中华蜜蜂种群遗传分化与环境适应机制研究进展. 昆虫学报 66, 1258-1270.
47. 郑飞，郭欣，郭博洋，黄贤亮，陈兵. 2022. 白洋淀及周边土壤重金属的分布特征及生态风险评估. 环境科学 43, 265-274
48. 郑飞，郭欣，郭博洋，黄贤亮，陈兵. 2021. 重金属污染评估及其生物健康效应. 中国科学: 生命科学 64, doi: 10.1360/SSV-2021-0318.
49. 芦超，丁玎，陈兵. 2020. 昆虫对环境低氧的适应：生理和分子机制研究进展. 环境昆虫学报, 42(1): 82-93
50. 陈兵. 2019. 环境胁迫适应的生态基因组学. 见：生态基因组学, 康乐主编. 北京: 科学出版社, pp 83-97
51. 陈兵，康乐. 2016. 生态基因组学与分子适应. 见：生态学的现状与发展趋势, 于振良主编. 北京: 科学出版社, p42-53
52. 陈兵，康乐. 2013. 表型可塑性研究. 见：新生物学年鉴2013, 新生物学年鉴编委会主编. 北京：科学出版社, p128-155
社会服务工作：
中国昆虫学会直翅类昆虫专业委员会，副主任（2023-2026）
中国昆虫学会昆虫生理生化与分子生物学专业委员会，委员（2023-2026）
《昆虫学报》，编委（2021-2025）
《环境昆虫学报》，编委（2019-2027）
《Frontiers in Ecology and Evolution》，Associate Editor（2022年至今）。
项目评阅专家：国家自然科学基金委、浙江省自然科学基金委、科技部科技评估中心、波兰国家科学中心（the National Science Centre Poland）项目评审专家。
国际杂志审稿人:审稿超过20个国际期刊，包括Ecology Letters, PNAS Nexus, Molecular Ecology, Communications Biology, Heredity, BMC Genomics, Frontiers in Genetics等。
国际会议组委会秘书长，The International Conference on Insect Science in 2023(2023年国际昆虫学大会)，2023年8月6-10日，中国保定
研究生招生：
硕士研究生招生专业：071010生物化学与分子生物学
博士研究生招生专业：071000生物学
欢迎有兴趣的考生咨询和报考！
