个人简介
赵立宁,女,1991年10月生,河北邢台人,博士,校聘副教授。
主要从事环境化学污染物诱发疾病相关氧化应激、信号通路、免疫失衡等的毒性效应与机理;在基于蛋白质或分子水平上研究暴露标志物和健康效应生物标志物指标体系、评价技术和方法、危害阻断技术及预防对策;在细胞和机体水平上,进行污染物对机体损伤评估的研究;开展废物处理与资源化技术、清洁生产审核等环保相关咨询服务工作。
目前主持省部级、校级课题5项,在International Journal of Biological Macromolecules、Science of the total environment、Ecotoxicology and Environmental Safety等期刊发表SCI论文20余篇,第一或通讯作者SCI论文10余篇。
教育经历:
2014.09-2019.06 山东大学 环境科学专业, 获工学博士学位
2010.09-2014.06 山东大学 环境科学与工程专业,获工学学士学位
工作经历:
2019.09-至今 河北大学生命科学学院 校聘副教授
讲授主要课程
细胞生物学实验(本科生)
近五年论文发表:
1. Xinyu Ni; Yudie Lu; Meiyu Li; Yue Liu; Miao Zhang; Fuqiang Sun; Sijun Dong*; Lining Zhao*, Application of Se-Met to CdTe QDs significantly reduces toxicity by modulating redox balance and inhibiting apoptosis,Ecotoxicology and Environmental Safety, 2023, 267: 115614.
2. Nana Ma; Yudie Lu; Jing Wang; Xueyou Liang; Sijun Dong; Lining Zhao*,Role of CdTe quantum dots on peripheral Immunocytes and selenoprotein P: immunotoxicity at the molecular and cellular levels,Toxicology Research, 2023, 12(6): 1041-1050.
3. Zongshan Zhao; Haimei Li; Jiaqiang Yao; Jing Lan; Yan Bao;Lining Zhao; Wansong Zong; Qing Zhang; Henner Hollert; Xingchen Zhao,Binding of Tetrabromobisphenol A and S to Human Serum Albumin Is Weakened by Coexisting Nanoplastics and Environmental Kosmotropes,Environmental Science & Technology, 2023 Mar 21;57(11):4464-4470.
4. Nana Ma; Diao Ma; Xia Liu;Lining Zhao; Lei Ma; Dan Ma; Sijun Dong, Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway, Environment International, 2023 May:175:107949.
5. Xinyu Ni; Miao Zhang; Jing Zhang; Zhen Zhang; Sijun Dong*; Lining Zhao*, Molecular mechanism of two functional protein structure changes under 2,3-butanedione-induced oxidative stress and apoptosis effects in the hepatocytes, International Journal of Biological Macromolecules, 2022 Oct 1:218:969-980.
6. Xingchen Zhao; Penghui Li; Shanjun Song; Huiyu Wang;Lining Zhao; Wansong Zong; Haiyan Zhang; Guangbo Qu; Ligang Hu; Zongwei Cai; Guibin Jiang, Molecular structural heterogeneity of bisphenols governs their serum albumin binding, Science of The Total Environment, 2021,781,146499.
7. 陈博,赵立宁*,董四君*,白洋淀生态环境的演变,中国科学·生命科学,2021,51(9):1274-1286.
8. Hao Zhang; Lingyu Luan; Mengjiao Bi;Lining Zhao; Lin Yuan; Jia Feng; Rutao Liu, In vivo and in vitro studies on inactivation of selenium containing protein- glutathione peroxidase 3 in mice nephrocytes caused by lead, Ecotoxicology and Environmental Safety, 2020,203,111008.
9. Lining Zhao; Zihan Guo; Hongxin Wu; Yan Wang; Hao Zhang*; Rutao Liu*, New insights into the release mechanism of Cd2+ from CdTe quantum dots within single cellsin situ, Ecotoxicology and Environmental Safety, 2020,196:110569.
10. Lining Zhao;Wansong Zong; Hao Zhang*; Rutao Liu*, Kidney Toxicity and Response of Selenium Containing Protein-glutathione Peroxidase (Gpx3) to CdTe QDs on Different Levels, 2019,1(168):201-208.
11. Lining Zhao;Dandan Guo; Jing Lin; Rutao Liu*,Responses of catalase and superoxide dismutase to low-dose quantum dots on molecular and cellular levels,Ecotoxicology and Environmental Safety, 2019,181:388-394.
12. Lining Zhao;Hao Zhang; Jing Zhang; Wansong Zong; Rutao Liu*, Spectroscopic characterization, calorimetric study and molecular docking to evaluate the bioconjugation of maltol with hemoglobin, Luminscence, 2019,2(34):290-296.